Multivalent import platform(MVIP)

    Multivalent import platform(MVIP)

    Fully independent intellectual property rights. Kylonova's Multivalent Import Platform (MVIP) is a specific delivery system for hepatic disease treatments constructed using the hepatic parenchymal cells of the Asialoglycoprotein receptor (ASGPR).

    General Formula:

    (X-L)n-B-D-T 

    Wherein:

    ※        X is a target-specific ligand

    ※        L is a branch of a sterically stabilized structure

    ※        B is a connector

    ※        D is a linker

    ※        T is a drug

    ※        n is an integer from 1 to 15


     

    Multivalent Import Platform (MVIP) has the following features:

    ●  It has been applied to siRNA drugs. Pre-clinical subcutaneous injection test has been finished. It has active liver targeting, stability and good biodegradability.

    ●  Applicable to small molecule drugs, the pre-clinical intestinal drug administration has been verified, which can avoid the whole-body intake of drugs and reduce the toxic side effects on other organs.

    ●  Low production costs, can be produced in bulk, and sold commercially.


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